Dr. Kaushik Rajaram

Dr. Kaushik Rajaram

Name: Dr. Kaushik Rajaram
Designation: Assistant Professor
Phone: 04366-277230
Email: rkaushik@cutn.ac.in


Biographic Sketch:
Dr Kaushik Rajaram did his Post Graduation (MSc) in Microbiology from Madurai Kamaraj University, Madurai, Tamil Nadu. And he completed his PhD at Hasselt University, Belgium in the field of Biomedical science and he developed Dual phage display biosensors for the rapid and early diagnosis of auto-immune disease (multiple sclerosis), followed by he worked as a research assistant at the reputed Trinity College Dublin, Ireland in the field of antibody library and phage display. And then he worked as a National Postdoctoral fellow at the Indian Institute of Science, Bangalore in the field of molecular diagnostics. In the year 2017 December, he joined as an Assistant Professor of Microbiology at the Central University of Tamil Nadu. Currently, he is running a nano-biomaterials and Phage lab, and he is guiding 3 PhD students and completed 16 MSc dissertations. He has published 15 research articles, 7 book chapters and 1 patent (published) in his credit.

Research Highlights :

Dr. Kaushik Rajaram's lab is focussing on Antimicrobial Resistance (AMR) and work on antimicrobial nanomaterials, polymers, phage and antimicrobial peptides. His lab also develops scaffolds for wound healing, consisting of antimicrobial materials and wound healing promotors. They also work on phage combinations, and efflux pump inhibitors to potentiate the antibiotics.  

Recent Publications :

1. Deeksha SarojiniDevi Radhakumar, Sundar Thiyagarajan, Kaushik Rajaram, Rajesh Parsanathan. Human antimicrobial peptide Histatin 1, 3, and its autoproteolytic cleaved peptides target the monkeypox virus surface proteins: molecular modelling and docking studies. Research square (preprints). https://doi.org/10.21203/rs.3.rs-3000084/v1. 

2. L. Priyadarsini, A. Subbiah, S. Srivignesh, K. Rama Krishna, K. Rajaram, S.Kathiresan, A. Ramesh Kumar. Comparative analysis of growth and yield parameters of grape var Muscat Hamburg grafted on Dog Ridge rootstock and self-rooted cuttings. Plant Archives. 23,1, 2023 pp.384-388. https://doi.org/10.51470/PLANTARCHIVES.2023.v23.no1.063

3. Anh. H. Nguyen, Sojin Song, Ha. T. Do,, Lan N. Mai, Thuat T. Trinh, Kaushik Rajaram*. Rapid and Duplex Detection of MRSA using SERS-based Molecular Beacons. Nano Trends.   2023, 2, 100007. https://doi.org/10.1016/j.nwnano.2023.100007

4. Thillaichidambaram Muneeswaran, Muthuchamy Maruthupandy, Aarcha Shanmugha Mary, Thirumalaiswamy Vennila, Rajaram Kaushik, Chockalingam Muthiah Ramakritinan, Franck Quero. Starch-mediated synthesis of chitosan/silver nanocomposites: in-vitro antibacterial and wound healing applications. Journal of Drug Delivery science and Technology.  2023, 84, 104424, https://doi.org/10.1016/j.jddst.2023.104424.(IF: 5.21).

5. Nithya Selvaraju, Senthilnathan Selvaraj, Neeraj Singhal, Vigneshwaran Mohan, Yuvaraj Sivalingam, Kaushik Rajaram, Gunasekaran Venugopal. Electron Transfer Behaviour of Green Synthesized Carbon Quantum Dot Sensor Towards VOC and Heavy Metal Ion Sensing. Materials Science Engineering B. (2022-Accepted). (IF: 4.10).

6. Nashath Kalangadan#, Aarcha Shanmugha Mary#, Rudrapogu Hepsiba Jyothi#, Sathyanarayanan Punniyakoti, Srivigensh Sundaresan, Ramesh Kumar Alagarsamy, Kaushik Rajaram*. Characterization and antimicrobial evaluation of green synthesized silver nanoparticle thin films with reusable applications. Materials Letter. 2022, https://doi.org/10.1016/j.matlet.2022.131923. (IF: 3.5).

7. Aarcha Shanmugha Mary, Vikram Srinivasa Raghavan, Sirisha Kagula, Vinodhini Krishnakumar, Meganathan Kannan, Sai Siva Gorthi, Kaushik Rajaram*. Enhanced In Vitro Wound Healing Using PVA/B-PEI Nanofiber Mats: A Promising Wound Therapeutic Agent against ESKAPE and Opportunistic Pathogens. ACS applied biomaterials. 2021, 4, 12, 84668476. https://doi.org/10.1021/acsabm.1c00985. (IF 4.09).

8. DC Dinesh, S Tamilarasan, K Rajaram, E Boua. Antiviral Drug Targets of Single-Stranded RNA Viruses Causing Chronic Human Diseases. Current drug targets. 2020;21(2):105-124. doi: 10.2174/1389450119666190920153247. (IF: 3.8).

9. Behera SK, Das D, Balasubramani K, Chellappan S, Rajaram K, Mohanta HK, Balabaskaran Nina P (2020) Seroprevalence and risk factors of brucellosis in livestock in the wildlife and livestock interface area of Similipal Biosphere Reserve, India, Veterinary World, 13(3): 465-470. Doi.org/10.14202/vetworld.2020.465-470 H. (IF: 2.1)

10. Guguloth, S. K., Lakshmi, A. R., Rajendran, R., Rajaram, K., Chinnasamy, T., Huang, J. D., ... & Durairajan, S. S. K. A Mechanistic Review on Plant-derived Natural Inhibitors of Human Coronaviruses with Emphasis on SARS-COV-1 and SARS-COV-2. Current drug targets. 2021 DOI: 10.2174/1389450122666211005115313. (IF: 3.8)

11. Durairajan, S. S. K., Selvarasu, K., Bera, M. R., Rajaram, K., Iyaswamy, A., & Li, M. Alzheimer's Disease and other Tauopathies: Exploring Efficacy of Medicinal Plant-Derived Compounds in Alleviating Tau-Mediated Neurodegeneration. Current molecular pharmacology. 2021. DOI: 10.2174/1874467214666210906125318.(IF: 3.7)

12. Kaushik Rajaram, Patricia Losada-Pérez, Veronique Vermeeren, Baharak Hossenikhani, Patrick Wagner, Veerle Somers, Luc Michiels. Real time analysis of dual display phage immobilization and autoantibody screening using quartz crystal microbalance with dissipation monitoring. International journal of nanomedicine. 2015; 10, 5237-5247. (IF: 7.4)

13. Kaushik Rajaram, Vermeeren V, Somers K, Somers V, Michiels L. Construction of a helper plasmid-mediated dual-display phage for autoantibody screening in serum. Applied Microbiology and Biotechnology. 2014; 98(14):6365−6373. (IF: 5.9)

14. Vasuki V, Sugeerappa L H, Nagalakshmi K, Somnath G, Kaushik Rajaram.  Optimisation of an asymmetric polymerase chain reaction assay for the amplification of single-stranded DNA from Wuchereria bancrofti for electrochemical detection. Mem Inst Oswaldo Cruz, Rio de Janeiro, Vol. 108(6): 804-807, September 2013. (IF: 1.9)

15. D Yuvaraj, Kaushik Rajaram, and K. Narasimha Rao. Optical, Field-Emission, and Antimicrobial Properties of ZnO Nanostructured Films Deposited at Room Temperature by Activated Reactive Evaporation. ACS Applied. Materials. Interfaces, 2010, 2(4), pp10191024 (IF 10.1).

16. S. Ghosh, Kaushik Rajaram, K. Nagalakshmi , S. L. Hoti , G. A. Menezes, B. N. Harish, H. N. Vasan. Antimicrobial activity of highly stable silver nanoparticles embedded in agar agar matrix as a thin film. Carbohydrate Research. 345 (2010) 2220 2227. (IF- 2.1).

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