Dr. Pahwa’s research group is keen to exploit supramolecular chemistry mediated host-guest interactions to advance a wide array of biological applications in the field of therapeutic, sensing and diagnostic. Furthermore, her research group explores molecular recognition between supramolecular probes and nanomaterials, aiming to accomplish:

• Development of high throughput sensors by utilising array based sensing (chemical nose) approach to discriminate various bioanalytes
• Spatially and temporally controlled therapeutics
• Design and development of bioinspired nanosystems for templated organic synthesis
• Reversible self-assembled systems as smart materials

1.     R. Sasmal, A. Som, P. Kumari, M. Pahwa, N. D. Saha, S. Rao, V. Sheeba, S. S. Agasti; “Supramolecular catch-and-release strategy for bioorthogonal fluorogenic imaging across the visible spectrum”, bioRxiv, 2023.

2.     N. Das Saha, S. Pradhan, R. Sasmal, A. Sarkar, C. M. Berač, J.C. Kölsch, M. Pahwa, S. Show, Y. Rozenholc, Z. Topçu, V. Alessandrini, J. Guibourdenche, V. Tsatsaris, N. G. Eilstein, S. S. Agasti; “Cucurbit[7]uril Macrocyclic Sensors for Optical Fingerprinting: Predicting Protein Structural Changes to Identifying Disease Specific Amyloid Assemblies”, JACS, 2022, 144, 14363-14379.

3.     M. Pahwa, P. Jain, N. Das Saha, C. Narayana and S. S. Agasti, “Interfacial Tetrazine Click Chemistry Mediated Assembly of Multifunctional Colloidosomes” Chem. Commun., 2021, 57, 9534-9537.

4.     A. Som, M. Pahwa, S. Bawari, N. Das Saha, R. Sasmal, M. S. Bosco, J. Mondal, and S. S. Agasti, “Multiplexed Optical Barcoding of Cells via Photochemical Programming of Bioorthogonal Host-Guest Recognition” Chem. Sci., 2021, 12, 5484-5494.

5.     M. Pahwa, M. Sharma, S. K. Meethal and S. S. Agasti, “Reversible Regulation of Esterase Activity via Host–Guest Molecular Recognition at the Nanoparticle Surface” Bull. Mater. Sci., 2020, 43, 1-7.

6.     R. Sasmal, N. Das Saha, M. Pahwa, S. Rao, D. Joshi, M. S. Inamdar, V. Sheeba and S. S. Agasti, “Synthetic Host–Guest Assembly in Cells and Tissues: Fast, Stable, and Selective Bioorthogonal Imaging via Molecular Recognition” Anal. Chem., 2018, 90, 11305-11314.

7.     S. K. Meethal, R. Sasmal, M. Pahwa, S. Chandrasekhar, N. Das Saha and S. S. Agasti, “Cucurbit[7]uril Directed Assembly of Colloidal Membrane and Stimuli Responsive Microcapsules at the liquid-liquid Interface” Langmuir, 2018, 34, 693-699.

Book chapter:

1.     M. Pahwa, Athira M. P. and S. S. Agasti; “Organic/Inorganic Hybrid Nanostructures for Biological Imaging and delivery” Encyclopedia of Nanomaterials, Elsevier, 2023, V2, 478-495.: