Prof. N. Gopalan

Prof. N. Gopalan

Name: Prof. N. Gopalan
Designation: Professor
Phone: 04366-277230
Email: gopalan@cutn.ac.in

 

Biographic Sketch:
As Professor Head of EPH, educate people to disease management like cancer awareness, insect borne diseases, food and water borne diseases and general higness of environment New Process preparation of large scale recombinant proteins for Therapeutic and diagnosis purposes, develop novel therapeutic paradigms to inflammation for digestive diseases like colon and pancreatic cancers,Edible/environmentally degradable Cutlery,Storage pests management using Phytochemicals and Essential oil,Value addition of food products. I have 37 years of experience of research and development in multidisciplinary fields and have nearly two decades of familiarity in the subject of Technology and Business development due to my active involvement in Planning and Technical Co-ordination, Project Management, Product Development, Human Resource Development and Scientific Administration. I have in my crediate 1I2publication and 12 patents. Guidend 24 MSc students for their dissertation work and 4 PhD students as wellas guiding 8 PhD students.i have handeld 12 DRDO projects and 2 ongoing projects from DST and ICMR. I am committed team builder, leader and team player who enjoy challenges and responsibilities. I can add real value and make a worthwhile contribution to the growth of a university Departments with technical and administrative essentials gained in DRDO.

   
Research Highlights :

Work on insect repellent -Diethyl Phenyl Acetamide (DEPA):

Inclusion in Indian Pharmacopoeia

Technology transfer to major  07 firms

 

Work on malarial parasite aspects:

Four  papers published in  Analyst,  Journal of Industrial Microbiology and 

Biotechnology, parasitology Research and Hybridoma. 

 Development of malarial detection kit

Completed two student s for Ph.D thesis and Two Students for their M.Sc dissertation work.

Best Paper award- 2010

Detection  of Carboxylesterase Isoenzymes and Altered Acetylcholinesterase during insecticidal Resistance in Mosquito

Four  papers published in  Pestcide biochemistry and Physiology,  IJMR, parasitology  

Developemnt field based filter paper spot test kit, been used by DRLT, all field

Two paptents

Cancer biology:

Two manuscripts published in  Oncogene (NPG), Two manuscript in Gastroentrology, Four manuseripts in Am J Physiol Gastrointest Liver Physiol

Ten abstracts were presented in international conferences of Digestive Diseases Week and American Association of Cancer Biology.

Awarded the prestigious GRG/AGA fellow 

 

Attracticide:

Indian and multinational patents filed (European, US patent)

Technology transferred to  company of C21 as attracticide for large scale production

Chikungunya:

Chikungunya has emerged as one of the most important arboviral infection of global significance.

Dengue:

Five manuscripts published in Virus Genes, Indian Journal of Medical Microbiology, The Scientific World Journal, Journal of Virological Methods and Indian Journal of Pediatrics

Development of First Aid Kit:

Achievements:

Three manuscripts published in Drug Toxicology and Metabolism, Pharmaceutical Biology, Journal Environmental Toxicology

Indian Design patents for First Aid Kit and Formulation Patent

Technology transferred to  company

Obtained Licenses for tablets and formulations

 

Work on Scale Up and Drug filling:

Obtainied GMP certificate from FDA for Scale-up facility:

Achievements:

Obtained GMP Certificates from FDA  for Drug filling for Bioprocess Scale-up Facility at DRDE, Gwalior

Obtained certificates for individuals for QA and QC from FDA

Obtained pollution free certificate from MP Pollution Board for Scale-up facility



Recent Publications :

Pandit C, Alajangi HK, Singh J, Khajuria A, Sharma A, Hassan MS, Parida M, Semwal AD, Gopalan N, Sharma RK, Suttee A, Soni U, Singh B, Sapra S, Barnwal RP, Singh G, Kaur IP Development of magnetic nanoparticle assisted aptamer-quantum dot based biosensor for the detection of Escherichia coli in water samples. Sci Total Environ. 2022, 20;831:154857. doi: 10.1016/j.scitotenv.2022.154857.

Yilma Markos Larebo, Legesse Tesfaye Elilo, Desta Erkalo Abame, Denebo Ersulo Akiso, Solomon Gebre Bawore, Abebe Alemu Anshebo, Natarajan Gopalan. Awareness, Acceptance, and Associated Factors of Human Papillomavirus Vaccine among Parents of Daughters in Hadiya Zone, Southern Ethiopia: A Cross-Sectional Study. Vaccines (Basel) 2022  10(12): 1988.  doi: 10.3390/vaccines10121988

Indumathi Mohan, Naveen Kumar Kodali, Savitha Chellappan, Balasubramani Karuppusamy, Sujit Kumar Behera, Gopalan Natarajan, Praveen Balabaskaran Nina. Socio-economic and household determinants of malaria in adults aged 45 and above: analysis of longitudinal ageing survey in India, 2017–2018. Malar J. 2021; 20: 306. doi: 10.1186/s12936-021-03840-w

Deshetty UM, Tamatam A, Bhattacharjee M, Perumal E, Natarajan G, Khanum F. Ameliorative Effect of Hesperidin Against Motion Sickness by Modulating Histamine and Histamine H1 Receptor Expression. Neurochem Res. 2020 Feb;45(2):371-384. doi: 10.1007/s11064-019-02923-0.
 
Xavier JR, Madhan Kumarr MM, Natarajan G, Ramana KV, Semwal AD.  Optimized production of poly (γ-glutamic acid) (γ-PGA) using Bacillus licheniformis and its application as cryoprotectant for probiotics. Biotechnol Appl Biochem. 2020 ;67(6):892-902. doi: 10.1002/bab.

P. Rachitha, K. Krupashree, G.V. Jayashree, Hemanth Kumar Kandikattu, Narayanappa Amruta, Natarajan Gopalan, M.K. Rao, Farhath Khanum Chemical composition, antioxidant potential, macromolecule damage and neuroprotective activity of Convolvulus pluricaulis. J Tradit Complement Med. 2018 Oct; 8(4): 483–496. doi: 10.1016/j.jtcme.2017.11.002.

Kalagatur, Chandranayaka Siddaiah, Venkataramana Mudili, Kadirvelu Krishna, Gopalan Natarajan, Venkata L. Rao Putcha. Antifungal and Zearalenone Inhibitory Activity of Pediococcus pentosaceus Isolated from Dairy Products on Fusarium graminearum. Muthulakshmi Sellamani, Naveen K.. Front Microbiol. 2016; 7: 890.  doi: 10.3389/fmicb.2016.00890.

Dash PK, Agarwal A, Sharma S, Saha A, Joshi G, Gopalan N, Sukumaran D, Parida MM Development of a SYBR green I-based quantitative RT-PCR for Ross River virus: Application in vector competence studies and antiviral drug evaluation. Virol Methods. 2016 Aug;234:107-14. doi: 10.1016/j.jviromet.2016.04.011

A Shrivastava, M Soni, S. Shrivastava, S Sharma, PK Dash, N Gopalan, PK Behera, MM Parida. Lineage shift of dengue virus in Eastern India: an increased implication for DHF/DSS. Epidemiol Infect. 2015 Jun; 143(8): 1599–1605.  doi: 10.1017/ S0950268814002751.

Priyanka Chahar, Manjeri Kaushik, Sarvajeet Singh Gill, Surendra Kumar Gakhar, Natrajan Gopalan, Manish Datt, Amit Sharma, Ritu Gill.Genome-Wide Collation of the Plasmodium falciparum WDR Protein Superfamily Reveals Malarial Parasite-SpecificFeatures.PLoSOne. 2015; 10(6). doi: 10.1371/journal.pone.0128507.

Sripathi M. Sureban, Randal May, Satish Ramalingam, Dharmalingam Subramaniam, Gopalan Natarajan, Shrikant Anant, Courtney W. Houchen Selective Blockade of DCAMKL-1 Results in Tumor Growth Arrest by a Let-7a MicroRNA-Dependent Mechanism.. Gastroenterology. 2009:137(2): 649–659.e2.  doi: 10.1053 /j.gastro. 2009.05.004.



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